Recently launched Nytol liquid offers easy to swallow formulation containing a sedative antihistamine, diphenhydramine hydrochloride. Although liquid preparations containing diphenhydramine hydrochloride can be bought already (cough syrups), Nytol oral solution is the only product that contains diphenhydramine which is licensed as a sleep aid product. Initially, after the launch Nytol liquid was marketed also as an antihistamine, however, this indication was removed from Nytol. Nytol liquid review summarises product indications, age restrictions, and review of possible side effects. I will also talk about differences and similarities between Nytol liquid and Nytol tablets.