Irritable bowel syndrome (IBS) is a common condition which is characterised by smooth muscle spasm alongside the gastrointestinal tract with a range of associated symptoms. Patients who are diagnosed with IBS are usually advised on the lifestyles to minimise the risk of IBS symptoms. Review of diet and lifestyle is one of the first recommendations gives by a doctor once a patient is diagnosed with IBS. Drug treatment can be used alongside lifestyle measures. Most of the drugs which are recommended in the symptomatic management of IBS can be purchased over the counter from pharmacies, supermarkets and online. Today I will review 14 best IBS medication over the counter.